A to Z of CBD

    What is CBD? A panel of industry experts at the 2019 TPE show explored the popular new product category that is sweeping retail and provided the basic information retailers should know before bringing CBD products into their stores.

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    A to Z of CBD

    At the 2019 Tobacco Plus Expo (TPE), which was held in February in Las Vegas, Nevada, a panel of experts who are currently working in the cannabidiol (CBD) industry took on the basic questions surrounding the growing popularity of CBD. The panel included Bianca Iodice, president of Purilum; Brian Moyer, CEO of Criticality; Jose Martinez, chief technical officer of Criticality; and Christian Cypher, senior vice president of global specialty products and managing director of specialty crops at Pyxus International.

    Brian Moyer and Jose Martinez of Criticality
    Brian Moyer and Jose Martinez of Criticality

    So, what is CBD? CBD is a natural, bioactive, non-psychoactive chemical compound found in cannabis sativa and industrial hemp plants. According to Moyer, CBD is most prevalent in industrial hemp. The fact that CBD is not psychoactive is a very important difference because it is this element that sets hemp and marijuana apart from one another in the eyes of the U.S. government as well as when it comes to federal and state regulations.
    “The main difference between marijuana and industrial hemp is the amount of THC that’s found in industrial hemp,” Moyer explained. “Industrial hemp, by definition, has below 0.3 percent THC, and thus there is no ‘high’ associated with hemp like there is on the marijuana side.”

    In many states, there’s a thin line between what constitutes a CBD product and what constitutes a marijuana product—and it often comes down to how much THC is present in the specific product being sold. “THC and CBD are both separate cannabinoids that are ➤ found in the industrial hemp plant,” Moyer went on to explain. “CBD products that are made from a hemp oil extract can have up to 0.3 percent THC in the final product. Anything that exceeds that is not permissible under federal and most state laws. So oil-based products can have some THC. Some products are made out of what’s called isolate, or purified CBD. In those cases, there’s no THC in those products. Those are THC-free products.”

    The Legal Status of CBD
    CBD interacts with the human body through the endocannabinoid system, which is a system of receptors found throughout the body that regulate such things as mood, appetite, stress and other functions. People can consume CBD in various ways, including inhalation, orally or via a topical product. For inhalation methods, CBD can come in the form of an e-liquid. For those who want to take CBD orally, tincture drops or capsules with different dosages of CBD are available. The topical form of CBD can be applied to the skin as a cream or a serum, which allows CBD to enter the body after being absorbed by the skin.

    Christian Cypher
    Christian Cypher

    While CBD is said to treat a number of issues ranging from pain to insomnia, there’s also a question of CBD’s classification. Is it a drug? At the TPE show, Cypher discussed the findings of a study conducted by San Diego State University that examined the various reasons people use CBD products. Some cited the treatment of pain, inflammation, insomnia and even anxiety, all symptoms that would be treated by different pharmaceutical drugs. So, is CBD a drug? No, and there’s currently only one drug on the market with the U.S. Food and Drug Administration’s (FDA) approval that contains CBD.

    “The FDA has approved one prescription drug for treatment of specific medical conditions that relate to epilepsy that contains CBD. All other CBD on the market is more similar to dietary supplements,” said Cypher. “The FDA also has purview of what CBD can be added to substances. [The regulatory agency is] in the process of working through that framework. As it stands right now, the only FDA-approved drug with CBD in it is Epidiolex from GW Pharmaceuticals.”

    Continuing the discussion of the legality of CBD at the federal level, the TPE panelists discussed the 2018 Farm Bill that President Donald Trump signed into law in December 2018. The Farm Bill is significant for the hemp industry because it made permanent the 2014 Farm Bill that made it legal for state pilot programs to grow hemp. The passage of the 2018 bill was important because it specifically separated marijuana and industrial hemp according to United States Drug Enforcement Administration codes. That separation is very important for the development of new products, and it ultimately defines how the FDA views hemp and will eventually regulate it.

    Because industrial hemp is now no longer a scheduled substance, it is off the list of controlled substances, which opens up the market ➤ for additional hemp-based products such as CBD. Each state must submit to the United States Department of Agriculture its own state plan for handling industrial hemp and CBD products, including information on how the state plans to grow and process hemp as well as how it will sell hemp products at retail stores. The most important takeaway is that it is now legal on the federal level to grow, process and sell hemp-based products unless individual states have implemented laws to the contrary.

    Bianca Iodice
    Bianca Iodice

    New Opportunities
    With CBD beginning to penetrate mainstream culture, there is a considerable amount of opportunity for both manufacturers and retailers that are looking to leap into the category. Martinez discussed the various forms of technology that manufacturers like Criticality can use to extract oils from hemp plants. Once extracted, these oils are then used in the formulation of tinctures or ingestible products such as capsules. There are additional steps that can be taken and different technology that can be used post-processing in order to refine the extracted oil to create a purer form of CBD.

    “Other technology that we are going to implement is what we call ‘chromatography,’” explained Martinez. “It’s usually used in analysis but also in production to purify each of the cannabinoids so that we are able to isolate CBD, CBG [and] THC and can tailor formulations based on the purity of ingredients.”

    As the hemp and CBD market continues to mature, the TPE panelists encouraged everyone interested in these products to do their research. There are plenty of products to choose from, but not all CBD products are manufactured using the same standards or adhering to the same level of quality. Quality should be a concern, and a product can and should be able to be traced back to the farm on which it was grown. While CBD has yet to fall under the review and full regulation of the FDA, all the panelists agreed that regulation is coming, and to some degree it’s needed to ensure retailers and consumers are receiving the best CBD products possible.

    This story first appeared in the July/August 2019 issue of Tobacco Business magazine. Members of the tobacco industry are eligible for a complimentary subscription to our magazine. Click here for details.

    – Story and photos by Antoine Reid, an editor and digital content director for Tobacco Business Magazine. You can follow him on Instagram @editor.reid.